Endocrine Abstracts

Interferon therapy for chronic hepatitis C infection has been associated with thyroid abnormalities. We sought to characterise the incidence of this in a cohort of treated hepatitis C patients receiving weekly pegylated interferon therapy in a tertiary Hepatology unit. Patients were scheduled to receive 24 or 48 weeks treatment with monthly thyroid function tests (TFTs). Data was collected from electronic treatment records of 154 consecutive patients and analysed by a single i...

Macroprolactinaemia is defined as hyperprolactinaemia with a predominance of macroprolactin. It is present in approx 15–36% of cases of hyperprolactinaemia. Controversy exists as to the clinical relevance of macroprolactinaemia with a number of short-term studies demonstrating fewer classical symptoms of hyperprolactinaemia. The long-term prognosis is unknown.We have previously reported the findings after 5 years follow-up of a cohort of 55 patients...